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\u52a8\u7269\u79d1\u5b66\u535a\u58eb | \u5b9a\u91cf\u9057\u4f20\u5b66\u4e0e\u57fa\u56e0\u7ec4\u8bc4\u4f30\u4e13\u5bb6\u5728\u5e38\u89c4\u9057\u4f20\u8bc4\u4f30\u7684\u5f00\u53d1\u4e0e\u7ba1\u7406\u4ee5\u53ca\u5148\u8fdb\u5206\u6790\u6d41\u7a0b\u7684\u5f00\u53d1\u65b9\u9762\u62e5\u6709\u4e30\u5bcc\u7ecf\u9a8c\uff0c\u5c06\u7edf\u8ba1\u6a21\u578b\u548c\u673a\u5668\u5b66\u4e60\u5e94\u7528\u4e8e\u590d\u6742\u6570\u636e\u96c6\uff08GWAS\u3001SNP \u6807\u8bb0\u3001\u7cfb\u8c31\u3001\u8868\u578b\uff09\u3002\u4f5c\u4e3a\u4fdd\u62a4\u548c\u9009\u62e9\u8ba1\u5212\u7684\u4e13\u5bb6\uff0c\u4ed6\u5c06\u4e25\u8c28\u7684\u79d1\u5b66\u6001\u5ea6\u4e0e\u624e\u5b9e\u7684\u7f16\u7a0b\u80fd\u529b\uff08SAS\u3001Python\u3001R\/Shiny\u3001Fortran\u3001AWK\uff09\u76f8\u7ed3\u5408\uff0c\u7528\u4e8e\u5927\u6570\u636e\u7ba1\u7406\u3002\u5728\u7ba1\u7406\u56fd\u9645\u7814\u7a76\u9879\u76ee\u65b9\u9762\u62e5\u6709\u6df1\u539a\u7ecf\u9a8c\u3002 \u5e38\u89c1\u95ee\u9898 \u5173\u4e8e\u6211\u4eec\u89e3\u51b3\u65b9\u6848\u7684\u4fe1\u606f \u6211\u4eec\u5728\u7814\u53d1\u3001\u755c\u7267\u4e1a\u53ca\u5176\u4ed6\u9886\u57df\u63d0\u4f9b\u5e7f\u6cdb\u7684\u89e3\u51b3\u65b9\u6848\u3002\u6211\u4eec\u7684\u4e13\u5bb6\u4e0e\u5408\u4f5c\u4f19\u4f34\u7d27\u5bc6\u5408\u4f5c\uff0c\u4ee5\u786e\u5b9a\u91cf\u8eab\u5b9a\u5236\u7684\u89e3\u51b3\u65b9\u6848\u3002 \u60a8\u53ef\u4ee5\u901a\u8fc7\u7f51\u7ad9\u4e0a\u7684\u8054\u7cfb\u8868\u5355\u4e0e\u6211\u4eec\u8054\u7cfb\uff0c\u6216\u76f4\u63a5\u5411\u6211\u4eec\u53d1\u9001\u7535\u5b50\u90ae\u4ef6\u3002\u6211\u4eec\u968f\u65f6\u4e3a\u60a8\u89e3\u7b54\u7591\u95ee\u5e76\u8ba8\u8bba\u60a8\u7684\u9700\u6c42\u3002 \u6211\u4eec\u63d0\u4f9b\u610f\u5927\u5229\u8bed\u3001\u82f1\u8bed\u3001\u8461\u8404\u7259\u8bed\u548c\u897f\u73ed\u7259\u8bed\u670d\u52a1\u3002\u6211\u4eec\u81f4\u529b\u4e8e\u786e\u4fdd\u6240\u6709\u56fd\u9645\u5ba2\u6237\u90fd\u80fd\u83b7\u5f97\u6700\u5927\u7684\u6c9f\u901a\u4fbf\u5229\u3002\" \/>\n\t\t<meta 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content=\"\u6211\u4eec\u63d0\u4f9b\u7ed3\u5408\u524d\u6cbf\u9057\u4f20\u5b66\u7814\u7a76\u3001\u751f\u7269\u6280\u672f\u548c\u8f6f\u4ef6\u5f00\u53d1\u7684\u521b\u65b0\u670d\u52a1\uff0c\u65e8\u5728\u89e3\u51b3\u590d\u6742\u7684\u755c\u7267\u4e1a\u6311\u6218\u3002\u6211\u4eec\u5c06\u5927\u6570\u636e\u8f6c\u5316\u4e3a\u57fa\u56e0\u7ec4\u8bc4\u4f30\u548c\u9884\u6d4b\u5de5\u5177\uff08\u4eba\u5de5\u667a\u80fd\u3001\u6570\u5b57\u5b6a\u751f\uff09\uff0c\u901a\u8fc7\u53ef\u6269\u5c55\u7684\u79d1\u5b66\u89e3\u51b3\u65b9\u6848\u4f18\u5316\u751f\u4ea7\u529b\u5e76\u6700\u5927\u5316\u52a8\u7269\u5065\u5eb7\u3002\u6211\u4eec\u7684\u4f18\u52bf\u4f55\u5728\uff1f\u6211\u4eec\u5c06\u79d1\u5b66\u76f4\u63a5\u5f15\u5165\u755c\u820d\u548c\u5de5\u4e1a\u6d41\u7a0b\uff1a\u5f00\u53d1\u5927\u89c4\u6a21\u5e94\u7528\u6280\u672f\uff0c\u964d\u4f4e\u8fd0\u8425\u6210\u672c\uff0c\u5e76\u4ee5\u53ef\u8861\u91cf\u7684\u7ed3\u679c\u548c\u786e\u5b9a\u7684\u65f6\u95f4\u8868\u52a0\u901f\u9057\u4f20\u6539\u826f\u3002\u91cf\u8eab\u5b9a\u5236\u7684\u89e3\u51b3\u65b9\u6848\uff0c\u4e13\u4e3a\u751f\u4ea7\u8005\u8bbe\u8ba1\u3002 \u6211\u4eec\u7684\u4f7f\u547d\u6211\u4eec\u662f\u9057\u4f20\u5b66\u4e13\u5bb6\u6211\u4eec\u7684\u4f7f\u547d\u662f\u5728\u9057\u4f20\u5b66\u548c\u57fa\u56e0\u7ec4\u5b66\u9886\u57df\u63d0\u4f9b\u521b\u65b0\u7684\u89e3\u51b3\u65b9\u6848\uff0c\u4e3a\u5408\u4f5c\u4f19\u4f34\u63d0\u4f9b\u9ad8\u8d28\u91cf\u7684\u6210\u679c\uff0c\u5e76\u4e3a\u79d1\u5b66\u7814\u7a76\u505a\u51fa\u8d21\u732e\u3002 \u6211\u4eec\u7684\u4ef7\u503c\u89c2\u8bda\u4fe1\u4e0e\u521b\u65b0\u6211\u4eec\u575a\u4fe1\u8bda\u4fe1\u3001\u900f\u660e\u548c\u521b\u65b0\u7684\u91cd\u8981\u6027\u3002\u6bcf\u4e00\u4e2a\u9879\u76ee\u90fd\u662f\u7a81\u7834\u6781\u9650\u5e76\u786e\u4fdd\u4e3a\u884c\u4e1a\u63d0\u4f9b\u5353\u8d8a\u6210\u679c\u7684\u673a\u4f1a\u3002 \u516c\u53f8\u4ecb\u7ecd \u6bcf\u4e00\u9879\u51b3\u7b56\u90fd\u7531\u771f\u6b63\u4e86\u89e3\u8be5\u884c\u4e1a\u7684\u4eba\u58eb\u63d0\u4f9b\u652f\u6301 Ferdinando Galluzzo \u521b\u59cb\u5408\u4f19\u4eba\u517c\u9996\u5e2d\u8d22\u52a1\u5b98 \u517d\u533b\u79d1\u5b66\u535a\u58eb | \u5b9a\u91cf\u9057\u4f20\u5b66\u4e0e\u7edf\u8ba1\u5efa\u6a21\u4e13\u5bb6\u5b9a\u91cf\u9057\u4f20\u5b66\u3001\u6570\u636e\u79d1\u5b66\u3001\u7edf\u8ba1\u5efa\u6a21\u548c\u755c\u7267\u5b66\u4e13\u5bb6\u3002\u5f00\u53d1\u7528\u4e8e\u5927\u6570\u636e\u5206\u6790\u548c\u5546\u4e1a\u667a\u80fd\u7cfb\u7edf\u7684\u673a\u5668\u5b66\u4e60\/\u6df1\u5ea6\u5b66\u4e60\u6a21\u578b\u3002\u4ed6\u7684\u5b9e\u8df5\u65b9\u6cd5\u5b9e\u73b0\u4e86\u9057\u4f20\u8bc4\u4f30\u6d41\u7a0b\u7684\u81ea\u52a8\u5316\uff0c\u5c06\u4eba\u4e3a\u9519\u8bef\u51cf\u5c11\u4e86 90%\u3002\u4ed6\u8d1f\u8d23\u9057\u4f20\u8bc4\u4f30\uff08\u4ece\u8868\u578b\u5230\u6307\u6570\u9a8c\u8bc1\uff09\u4ee5\u53ca\u8f6f\u4ef6\uff08\u4ece\u6570\u636e\u5e93\u5230\u4e91\u7aef\uff09\u7684\u6574\u4e2a\u5f00\u53d1\u5468\u671f\u3002 Marcos P G Rezende \u521b\u59cb\u5408\u4f19\u4eba\u517c\u6280\u672f\u603b\u76d1 \u52a8\u7269\u79d1\u5b66\u535a\u58eb | 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